apolipoprotein e — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T30998L	COG-1410 acetate	COG-1410 acetate(878009-24-6 Free base)	Apoptosis
	COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.
T30998	COG1410	COG-1410,COG 1410
	COG-1410 is an apolipoprotein E (apoE) peptide mimetic.
T27957	LY-465608	LY 465608
	LY-465608, a PPAR Agonist, inhibits macrophage activation and atherosclerosis in apolipoprotein E knockout mice.
T69456	Melagatran monohydrate
	Melagatran monohydrate is a thrombin inhibitor. Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes. Melagatran reduces advanced atherosclerotic lesion size and may promote plaqu...
T75778	COG 133 TFA
	COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a ...
T63355	BMS-309403 sodium
	BMS-309403 sodium is a potent, orally active, selective inhibitor of the adipocyte fatty acid binding protein (FABP4, aP2), demonstrating inhibitory constants (K i ) of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, re...
T36521	Alaproclate (hydrochloride)
	Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s =...

Cat No.	Product Name	Synonyms	Targets
T21383	D-Thyroxine	Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine	Others
	D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles.

Recombinant Proteins

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Expression System：

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Cat No.	Product Name	Species	Expression System
TMPJ-00805	Apolipoprotein E/APOE Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and ca...
TMPJ-00756	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His)	Human	Human Cells
	ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipo...
TMPK-00788	Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPK-00762	Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc)	Human	HEK293
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPK-00589	Apolipoprotein E/APOE4 Protein, Human, Recombinant (His)	Human	HEK293
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPK-00588	Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPK-00763	Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPH-03199	APOE Protein, Rabbit, Recombinant (His & Myc & SUMO)	Rabbit	E. coli
	APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plas...
TMPH-02421	APOE Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	E. coli
	APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plas...
TMPJ-01447	Apolipoprotein B-100/APOB Protein, Human, Recombinant (His)	Human	E. coli
	Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles ...
TMPJ-00158	Apolipoprotein A-I/APOA1 Protein, Human, Recombinant	Human	E. coli
	Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various...
TMPY-02686	PON3 Protein, Human, Recombinant (S50N, His)	Human	Baculovirus-Insect Cells
	PON3 was enriched in the mitochondria-associated membrane fraction of hepatocytes. PON3 deficiency resulted in impaired mitochondrial respiration, increased mitochondrial superoxide levels, and increased hepatic expressi...
TMPY-02748	LRP-10 Protein, Human, Recombinant (His)	Human	HEK293
	LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi...
TMPY-02653	LRP-10 Protein, Human, Recombinant (hFc)	Human	HEK293
	LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi...
TMPY-01732	LRPAP1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Receptor-associated protein (RAP) is a molecular chaperone for low-density lipoprotein receptor-related protein (LRP), which plays a key role in cholesterol metabolism. The lipoprotein receptor-related protein (LRP) is a...
TMPY-01233	LRPAP1 Protein, Human, Recombinant (His)	Human	HEK293
	Receptor-associated protein (RAP) is a molecular chaperone for low-density lipoprotein receptor-related protein (LRP), which plays a key role in cholesterol metabolism. The lipoprotein receptor-related protein (LRP) is a...
TMPK-01424	Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)	Human	HEK293
	HLA-E01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01423	Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293
	HLA-E01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01452	HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)	Human	HEK293
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01541	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01544	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01514	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01545	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...